AI-Driven Cloud-Native Microservices Framework for Secure Healthcare Prescription Automation, Software Reliability, and Scalable Deployment Optimization

Authors

  • SRIKANTH REDDY GUDI Cigna Evernorth Health Services Inc, Charlotte, North Carolina, USA. Author

DOI:

https://doi.org/10.64137/31078699/IJETET-V2I1P106

Keywords:

Artificial Intelligence, Cloud-Native Systems, Microservices, Healthcare Prescription Automation, Software Reliability, E-Prescribing, Cyber Security, Cabernets, Mops, Develops, Observability, Clinical Decision Support

Abstract

Healthcare prescription automation is increasingly dependent on interoperable clinical data exchange, cloud-native service orchestration, secure application programming interfaces, and dependable software delivery pipelines. However, current prescription automation platforms often treat clinical decision support, e-prescribing workflow execution, software reliability engineering, cybersecurity governance, and deployment optimization as separate concerns. This separation creates architectural fragmentation in environments where prescription requests must be clinically valid, auditable, resilient to distributed failure, compliant with privacy obligations, and scalable under fluctuating enterprise workloads. This paper proposes a conceptual AI-driven cloud-native microservices framework for secure healthcare prescription automation, software reliability, and scalable deployment optimization. The framework integrates modular prescription services, AI-assisted clinical and operational intelligence, policy-driven security controls, observability-centered reliability engineering, and container-based deployment automation into a unified architecture. The major contribution of this paper is not an empirical claim of clinical superiority, but a structured reference model for designing prescription automation platforms that can support high-assurance workflows in regulated healthcare environments. The study identifies practical gaps in existing approaches, including a weak linkage between prescription standards and runtime reliability, insufficient integration of defect prediction with development pipelines, limited explainability in AI-assisted prescription decisions, and fragmented governance across APIs, containers, and machine learning components. The paper further presents a comparative methodology, architectural layers, implementation considerations, expected analytical outcomes, risk limitations, and future research directions. The proposed framework can guide healthcare enterprises, cloud architects, software reliability engineers, and AI governance teams in designing secure, scalable, and auditable prescription automation systems without binding the architecture to a single vendor or proprietary platform.

References

[1] N. Dragoni et al., "Microservices: Yesterday, Today, and Tomorrow," Present and Ulterior Software Engineering, pp. 195–216, 2017, doi: https://doi.org/10.1007/978-3-319-67425-4_12.

[2] S. K. Gunda, "Advancing software fault detection: A comparative study of neural network architectures," PROCEEDINGS OF THE 2025 12TH INTERNATIONAL CONFERENCE ON MECHANICS, MATERIALS AND MANUFACTURING: ICMMM2025, p. 020212, Jan. 2026, doi: https://doi.org/10.1063/5.0298095.

[3] NIST, "The NIST Cyber Security Framework (CSF) 2.0," The NIST Cyber Security Framework (CSF) 2.0, vol. 2.0, no. 29, Feb. 2024, doi: https://doi.org/10.6028/nist.cswp.29.

[4] J. C. Mandel, D. A. Kreda, K. D. Mandl, I. S. Kohane, and R. B. Ramoni, "SMART on FHIR: a standards-based, interoperable apps platform for electronic health records," Journal of the American Medical Informatics Association, vol. 23, no. 5, pp. 899–908, Feb. 2016, doi: https://doi.org/10.1093/jamia/ocv189.

[5] S. D. Sivva, R. R. Thalakanti, S. S. G. Bandari, and S. D. R. Yettapu, "AI-Driven Decision Intelligence for Agile Software Lifecycle Governance: An Architecture-Centered Framework Integrating Machine Learning Defect Prediction and Automated Testing," International Journal of Emerging Trends in Computer Science and Information Technology, vol. 4, pp. 167–172, 2023, doi: https://doi.org/10.63282/3050-9246.ijetcsit-v4i4p118.

[6] M. Souppaya, J. Morello, and K. Scarfone, "Application container security guide," Application Container Security Guide, Sep. 2017, doi: https://doi.org/10.6028/nist.sp.800-190.

[7] S. K. Gunda, "A Hybrid Deep Learning Model for Software Fault Prediction Using CNN, LSTM, and Dense Layers," Communications in Computer and Information Science, pp. 282–290, Oct. 2025, doi: https://doi.org/10.1007/978-3-032-05144-8_21.

[8] U.S. Department of Health and Human Services, "The Security Rule," HHS.gov, Oct. 20, 2022. https://www.hhs.gov/hipaa/for-professionals/security/index.html

[9] N. Mutyam, "Graph-Based Modeling of Service Dependencies for Predicting Failure Propagation in Distributed Systems," International Journal of Multidisciplinary Evolutionary Research, vol. 5, no. 1, pp. 113–116, 2024, doi: https://doi.org/10.54660/ijmer.2024.5.1.113-116.

[10] B. Burns, B. Grant, D. Oppenheimer, E. Brewer, and J. Wilkes, "Borg, Omega, and cabernets," Queue, vol. 14, no. 1, pp. 70–93, Jan. 2016, doi: https://doi.org/10.1145/2898442.2898444.

[11] Center for Devices and Radiological Health, "Clinical Decision Support Software - Draft Guidance," U.S. Food and Drug Administration, 2019. https://www.fda.gov/regulatory-information/search-fda-guidance-documents/clinical-decision-support-software

[12] S. K. Gunda, "Comparative Analysis of Machine Learning Models for Software Defect Prediction," pp. 1–6, Oct. 2024, doi: https://doi.org/10.1109/icpects62210.2024.10780167.

[13] National Council for Prescription Drug Programs, SCRIPT Implementation Recommendations, Version 1.76, May 2026. https://ncpdp.org/NCPDP/media/pdf/SCRIPT-Implementation-Recommendations.pdf

[14] OWASP, "OWASP Top 10 API Security Risks – 2023," owasp.org, 2023. https://owasp.org/API-Security/editions/2023/en/0x11-t10/

[15] S. D. Sivva, "An End-to-End AI-Based Systems Engineering Paradigm for Lifecycle Governance, Predictive Quality Assurance, Automation Economics, and Cyber Security Intelligence," Journal of Frontiers in Multidisciplinary Research, vol. 4, no. 1, pp. 600–604, 2023, doi: https://doi.org/10.54660/.jfmr.2023.4.1.600-604.

[16] National Institutes of Health, “HL7® Releases FHIR® v5.0 | Data Science at NIH,” Nih.gov, 2023. https://datascience.nih.gov/content/hl7%C2%AE-releases-fhir%C2%AE-v50

[17] R. R. Thalakanti, "Enhancing Convergence in Fully Connected Neural Networks via optimized back propagation," 2025 2nd International Conference on Computing and Data Science (ICCDS), pp. 1–6, Jul. 2025, doi: https://doi.org/10.1109/iccds64403.2025.11209625.

[18] A. Verma, L. Pedrosa, M. Korupolu, D. Oppenheimer, E. Tune, and J. Wilkes, "Large-scale cluster management at Google with Borg," Proceedings of the Tenth European Conference on Computer Systems, Apr. 2015, doi: https://doi.org/10.1145/2741948.2741964.

[19] "ONC's Cures Act Final Rule," ASTP - Assistant Secretary for Technology Policy, Jan. 15, 2026. https://healthit.gov/regulations/cures-act-final-rule/

[20] M. Balerao, "A Converged Artificial Intelligence Architecture for Innovation, Software Lifecycle Optimization, and Cyber Security Risk Mitigation," International Journal of Multidisciplinary Futuristic Development, vol. 4, no. 1, pp. 117–120, 2023, doi: https://doi.org/10.54660/ijmfd.2023.4.1.117-120.

[21] S. K. Gunda, "Analyzing Machine Learning Techniques for Software Defect Prediction: A Comprehensive Performance Comparison," 2024 Asian Conference on Intelligent Technologies (ACOIT), pp. 1–5, Sep. 2024, doi: https://doi.org/10.1109/acoit62457.2024.10939610.

[22] NIST, "AI Risk Management Framework," Artificial Intelligence Risk Management Framework (AI RMF 1.0), vol. 1, no. 1, Jan. 2023, doi: https://doi.org/10.6028/nist.ai.100-1.

[23] A. Avizienis, J.-C. Laprie, B. Randell, and C. Landwehr, "Basic concepts and taxonomy of dependable and secure computing," IEEE Transactions on Dependable and Secure Computing, vol. 1, no. 1, pp. 11–33, Jan. 2004, doi: https://doi.org/10.1109/tdsc.2004.2.

[24] S. Amershi et al., "Software Engineering for Machine Learning: A Case Study," 2019 IEEE/ACM 41st International Conference on Software Engineering: Software Engineering in Practice (ICSE-SEIP), May 2019, doi: https://doi.org/10.1109/icse-seip.2019.00042.

[25] D. Sculley et al., "Hidden Technical Debt in Machine Learning Systems," Neural Information Processing Systems, 2015. https://papers.nips.cc/paper_files/paper/2015/hash/86df7dcfd896fcaf2674f757a2463eba-Abstract.html

[26] V. K. R. Mittamidi, "AI/ML Powered Intelligent Root Cause Analysis and Automated Remediation for Multi-System Data Integrity Issues," International Journal of AI, BigData, Computational and Management Studies, vol. 6, pp. 133–141, 2025, doi: https://doi.org/10.63282/3050-9416.ijaibdcms-v6i4p115.

[27] "Security," cabernets. https://kubernetes.io/docs/concepts/security/

[28] ISO, "ISO/IEC FDIS 25010," ISO, 2023. https://www.iso.org/standard/78176.html

[29] R. Kaushal, K. G. Shojania, and D. W. Bates, "Effects of Computerized Physician Order Entry and Clinical Decision Support Systems on Medication Safety," Archives of Internal Medicine, vol. 163, no. 12, p. 1409, Jun. 2003, doi: https://doi.org/10.1001/archinte.163.12.1409.

[30] Open Telemetry Specification 1.43.0, “Open Telemetry Specification 1.43.0,” Open Telemetry, 2019. https://opentelemetry.io/docs/specs/otel/

[31] "Introduction | Open Policy Agent," Openpolicyagent.org, 2025. https://openpolicyagent.org/docs

[32] Horizontal Pod Auto scaling, "Horizontal Pod Auto scaling," cabernets, Nov. 23, 2025. https://kubernetes.io/docs/concepts/workloads/autoscaling/horizontal-pod-autoscale/

[33] M. Nygard, "Release It!: Design and Deploy Production-Ready Software," Torrossa.com, pp. 1–376, Mar. 2025, Accessed: Mar. 19, 2025. [Online]. Available: https://www.torrossa.com/gs/resourceProxy?an=5241265&publisher=FZP531

[34] "Beyer, B., Jones, C., Petoff, J., and Murphy, N.R. (2016). Site Reliability Engineering: How Google Runs Production Systems. O'Reilly Media. - References - Scientific Research Publishing," Scirp.org, 2016. https://www.scirp.org/reference/referencespapers?referenceid=4019415

[35] B. McMahan, E. Moore, D. Ramage, S. Hampson, and B. A. y Arcas, "Communication-Efficient Learning of Deep Networks from Decentralized Data," proceedings.mlr.press, Apr. 10, 2017. https://proceedings.mlr.press/v54/mcmahan17a.html.

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Published

2026-03-01

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Section

Articles

How to Cite

AI-Driven Cloud-Native Microservices Framework for Secure Healthcare Prescription Automation, Software Reliability, and Scalable Deployment Optimization. (2026). International Journal of Emerging Trends in Engineering and Technology, 2(1), 33-41. https://doi.org/10.64137/31078699/IJETET-V2I1P106